M- Placenta-derived mesenchymal stromal cells as a treatment for refractory chronic gingivostomatitis in cats: eight cases (2018). Journal of Small Animal Practice. 2022.

M. Febre, N. Saulnier, P. Roux, F. Boutoille, N. Girard, C. Robert, R. Rakic, E. Rosset and
S. Maddens.

J – Biosafety evaluation of equine umbilical cord-derived mesenchymal stromal cells (UC-MSCs) by systematic pathogen screening in peripheral maternal blood and paired UC-MSCs

– Denys, A – Léon, A – Robert, C – Saulnier, N – Josson-Schramme, A – Legrand, L -Wimel, L – Maddens, S ? Pronost,

I – Differences in the intrinsic chondrogenic potential of equine umbilical cord matrix and cord blood mesenchymal stromal/stem cells for cartilage regeneration

– Rodolphe Rakic, Bastien Bourdon, Magali Demoor, Stéphane Maddens, Nathalie Saulnier, Philippe Galéra Scientific Reports. 2018.

H – RNA Interference and BMP-2 Stimulation Allows Equine Chondrocytes Redifferentiation in 3D-Hypoxia Cell Culture Model: Application for Matrix-Induced Autologous Chondrocyte Implantation

– Rodolphe Rakic, Bastien Bourdon, Magalie Hervieu, Thomas Branly, Florence Legendre, Nathalie Saulnier, Fabrice Audigié, Stéphane Maddens, Magali Demoor, Philippe Galera – Int. J. Mol. Sci. 2017

G – Intra- articular administration of xenogeneic neonatal Mesenchymal Stromal Cells early after meniscal injury down-regulates metal- loproteinase gene expression in synovium and prevents cartilage degradation in a rabbit model of osteoarthritis.

Saulnier N, Viguier E, Perrier-Groult E, Chenu C, Pillet E, Roger T, et al. Osteoarthr Cartil. 2015.

F – Canine placenta: A promising potential source of highly proliferative and immunomodulatory mesenchymal stromal cells?

Nathalie Saulnier, Julia Loriau, Marine Febre, Clément Robert, Rodolphe Rakic, Tancrède Bonte, Samuel Buff, Stéphane Maddens. Veterinary Immunology and Immunopathology. 2016.

E – Comparison of efficacy and safety of single versus repeated intra-articular injection of allogeneic neonatal mesenchymal stem cells for treatment of osteoarthritis of the metacarpophalangeal/metatarsophalangeal joint in horses: A clinical pilot study.

Carmelo Magri, Michael Schramme, Marine Febre, Eddy Cauvin, Fabrice Labadie, Nathalie Saulnier, Isé François, Antoine Lechartier, David Aebischer, Anne-Sophie Moncelet, Stéphane Maddens. Plos One. 29 Août 2019.

For Veterinarians only

For Veterinarians only

Ask your veterinarian for the price of a stem cell injection at his clinic.

Product Pipeline

Range Product Development & optimization Proof of Concept Pilot study Industrialisation /
Manufacturing
Pivotal study Approval Marketing Launch

CANIPREN

VBX-01
Canine osteoarthritis

VBX-01
Canine osteoarthritis

VBX-01
Canine osteoarthritis

CA0102
Atopic dermatitis

CA0103
Atopic dermatitis
Chronic
Inflammatory
Bowel
Disease

Range Product Development & optimization Proof of Concept Pilot study Industrialisation /
Manufacturing
Pivotal study Approval Marketing Launch

FELIPREN

FE0101
Gingivostomatitis

FE0102
Chronic kidney
failure

FE0103
Feline arthrosis

Range Product Development & optimization Proof of Concept Pilot study Industrialisation /
Manufacturing
Pivotal study Approval Marketing Launch

EQUIPREN
OMBISTEM

EQ0101
Equine arthrosis